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The cryptococcus is a common soil fungus found in the roosting sites of birds, especially pigeons Usually the respiratory tract is the portal of entry, less often the skin and mucous membranes The pathologic changes are those of a granulomatous meningitis; in addition, there may be small granulomas and cysts within the cerebral cortex, and sometimes large granulomas and cystic nodules form deep in the brain (cryptococcomas) The cortical cysts contain a gelatinous material and large numbers of organisms; the solid granulomatous nodules are composed of broblasts, giant cells, aggregates of organisms, and areas of necrosis Cryptococcal meningitis has a number of distinctive clinical features Most cases are acquired outside the hospital and evolve subacutely, like other fungal infections or tuberculosis A few of our cases have had an explosive onset, rendering the patient quite ill in a day.

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1. Pick the Symbols and Arrows tab. Concentrate on the area titled Arrowheads. First sets the arrowhead for the rst end of the dimension line. Second sets the arrowhead for the second end of the dimension line. In most cases, you would use the same arrowhead style for both ends of a dimension, but AutoCAD gives you exibility in case you need to make them different. Leader sets the arrowhead for quick leaders a leader type that is different than a multileader. 2. To the right of First, pick the down arrow and review the types of arrowheads available. Some companies and individual architects use ticks instead of arrows at the ends of dimension lines. It would be rare to use None, but AutoCAD gives you that option. As you learned in the previous chapter, Arrow size displays and sets the size of the arrow. You also learned how to change the appearance of center marks in the Center marks area. 3. Make changes to the settings in the Arrowheads area and notice how the sample drawing changes.

Lissencephaly Lissencephaly with cerebellar hypoplasia Lissencephaly (Miller-Dieker) or isolated lissencephaly X-linked lissencephaly with hypogonadism (Partington syndrome) Muscle-eye-brain disease Walker-Warburg Holoprosencephaly Double cortex Double cortex or X-linked lissencephaly Heterotopias Periventricular nodular heterotopia Tuberous sclerosis Tuberous sclerosis Fukuyama muscular dystrophy Schizencephaly Schizencephaly Microcephaly Microcephaly Microcephaly

In the majority of patients, the early complaints are headache, nausea, and vomiting; mental changes are present in about half In other cases, however, headaches, fever, and stiff neck are lacking altogether, and the patient presents with symptoms of gradually increasing intracranial pressure due to hydrocephalus (papilledema is present in half such patients) or with a confusional state, dementia, cerebellar ataxia, or spastic paraparesis, usually without other focal neurologic de cit Furthermore, large series of affected patients indicate that 20 to 40 percent of patients have no fever when rst examined (the gure applies to patients without AIDS); we suspect that more frequent measurement of temperature would give a greater incidence of fever Cranial nerve palsies are infrequent ndings Rarely, a granulomatous lesion forms in one.

next to CssClass in the Appearance directory, select input from the drop-down menu as shown in Figure 7-9.

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