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the injection site are seen in 25%, fever in 10 15%, and a localized maculopapular or vesicular rash in 5%; a smaller percentage develop a diffuse rash, usually with five or fewer vesicular lesions Spread of virus from vaccinees to susceptible individuals is possible, but the risk of such transmission even to immunocompromised patients is small and disease, when it develops, is mild and treatable with acyclovir Nonetheless, the vaccine, being a live attenuated virus, should not be given to immunocompromised individuals, including HIV-positive children and adults, or pregnant women It is contraindicated in persons allergic to neomycin For theoretic reasons, it is recommended that following vaccination salicylates should be avoided for 6 weeks (to prevent Reye s syndrome) Several unresolved issues remain, including the need for booster doses, whether universal childhood vaccination will shift the incidence of disease to adolescence or adulthood with the possibility of more severe disease, and whether vaccination might prevent development of herpes zoster

This factor caused Linux and free software tools to stay within the confines of research and universities and not make inroads into businesses, which they believed was preventing Linux and other free tools from growing The principles of the open software movement are enumerated in the Open Source Definition, which was originally based on the Debian Free Software Guidelines13 To illustrate these licensing issues, imagine that you would like to use Microsoft Word to document your programs, but its memory and disk requirements are excessively high for your machine Because you only use a subset of Word s features, you really need a scaled-down version of the program say, Word-Lite Under commercial software policies, you have limited options: you can upgrade your current machine by adding more disk space and memory, buy a new machine, or find another program that meets your needs.

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Waning cell-mediated immunity that occurs with aging increases the risk of reactivation of latent varicella virus, as does immunosuppression More than 90% of adults have been exposed to varicella and are at risk for developing herpes zoster Most cases of herpes zoster occur in those over the age of 60 years, and postherpetic neuralgia (a severe and debilitating sequela that can last months to years) occurs in about 30% of those over age 60 in whom herpes zoster develops Zostavax is a live attenuated varicella-zoster vaccine that contains 14 times as much virus as that used for varicella vaccination (see above) Compared with placebo, a single subcutaneous dose of vaccine significantly decreased the incidence of herpes zoster, the incidence of postherpetic neuralgia, and the severity and duration of pain in those in whom postherpetic neuralgia developed Adverse events were mild and limited to local reactions Although it is theoretically possible to transmit the virus to susceptible contacts, no such cases have been reported A single dose of zoster vaccine is recommended for adults 60 years of age or older whether or not they have had a prior episode of herpes zoster Because it is a live attenuated vaccine, it is contraindicated in those with a primary or acquired immunodeficiency state (leukemia, lymphoma, any malignant neoplasm affecting the bone marrow, HIV infection), in those taking immunosuppressive medications (including high dose corticosteroids), and in pregnant women Those with an anaphylactic type reaction to gelatin or neomycin should not receive the vaccine

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This is a potentially misleading error message. Control can fall through from one case label to another, but only if there is no code in the first case label.

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